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H704 prcd PRA (partnerlab)

Background

Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests.

Test specific information

This test is patented in certain countries. We offer our clients two options for this test because we are not allowed to perform the test in our laboratory.
Firstly, the test can be ordered through a licensee of the patent owner.
As a second option, the test can be forwarded to a partner laboratory in non-patented territory.

Between these two options, a price difference is in place which is caused by the royalties costs on the test. The tests performed by both labs are technical identical.

Age

The disease may show itself on different ages, in which it cannot be estimated when the first symptoms may show themselves. Differences may exist between littermates, and between breeds.

Throughput

Normally the result can be expected within 20 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.

Location of disease or trait

This disease mainly affects vision, and may result in blindness.

Breed dependence

This DNA test is available for the following breeds: American Cocker Spaniel , American Eskimo Dog , Australian Cattle Dog, Australian Labradoodle, Australian Shepherd, Australian Shepherd Miniature & Toy, Australian Stumpy Tail Cattle Dog, Australian Silky Terriër, Chesapeake Bay Retriever, Chinese Crested, Cockapoo, Dwarf Poodle, English Cocker Spaniel, Entlebucher Mountain Dogs, Finnish Lapphund , Golden Retriever, Goldendoodle, Karelian Beardog, Kuvasz, Lab/Golden Cross, Labradoodle, Labrador Retriever, Lapponian Herder, Markiesje, Miniature American Sheperd, Miniature and Toy Poodle , Moyen Poodle, Norwegian Elkhound, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog , Giant Schnauzer, Schipperke, Spanish Water Dog , Yorkshire Terrier, Swedish Lapphund , Portuguese Podengo Pequeno, English Springer Spaniel. Additional information is available in the Frequently Asked Questions (FAQ).

Sample type

For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Swab, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.

Result

An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.

An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.

An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.

Inheritance

This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).

Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease

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Dog

prcd PRA (partnerlab)

Code H704
€ 47,80 (incl. 21% VAT)
€ 39,50 (excl. VAT)
Quantity