An abnormal increase in the volume of muscle fibers is the cause of Muscular Hypertrophy (in contrast with Muscular Hyperplasie, in which the increase in muscle is caused by the number of muscle fibers). The genetic factor results in addition of about 20 percent muscle, resulting in higher carcass yield combined with leaner meat. The genetic factor is indicated as mh, and occurs frequently in Piedmontese and Belgian Blue cattle. In other breeds however, the same increase in muscle has been seen. In addition to the clear advantages, several disadvantages originate from e.g. complications at birth. In a random selection of double-muscled cattle, at least 7 genetic variants have been seen in the mystatin-gene. Genetic identification of mh is very complex.
Test specific information
The genetic factor is continuously present, and will always be visible.
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
The genetic factor has an effect on muscle. Depending on the effect, increase of muscle volume and quality may take place.
This DNA test is available for the following breeds: Belgian Blue, Piedmontese. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.
An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.
An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.
This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).
Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.
Severity of Disease
Genetic characteristics are not a disease.