R536 Fishy Off-Flavour (FMO3)

Background

Fishy off-flavour in milk is characterized by a distinct, unpleasant taste and smell, reminiscent of rotten fish. In 2003, research has shown that an inborn error of metabolism is causing this effect. The mutation causing Fishy Off-Flavour in milk has been shown to be surprisingly common in one breed of cattle. The Swedish University of Agricultural Sciences developed a test for the Fish-odour syndrome in cattle. This genetic test enables the identification of carriers using a DNA-test. Using the test results, the Fishy Off-Flavour in milk can be eliminated.

Test specific information

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Age

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Throughput

The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.

Location of disease or trait

Milk is present in the udder.

Breed dependence

For this test samples from all breeds are accepted.

Sample type

For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.

Result

An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.

An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.

An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.

Inheritance

This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).

Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease

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Code R536

Fishy Off-Flavour (FMO3)

Test variant