V576 Porcine Stress Syndrome (PSS)


In pigs, malignant hyperthermia (MH or PSS) leads to rapid post-mortem changes in muscle, resulting in a bad quality of meat. MH can be triggered by minor stress, such as loading, transport, sexual intercourse, high ambient temperature, or exposure to the anaesthetic halothane. This has led to the common name, Porcine Stress Syndrome. PSS was a major economic problem in many countries in the 1970s. In part, this was due to strong selection for increased leanness, which is associated with susceptibility to PSS. In 1991, it was established that PSS is due to a change in the gene for the calcium release channel in skeletal muscle (altered calcium flow).

Test specific information



The genetic factor is continuously present, and will always be visible.

Turn Around Time

The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.

Location of disease or trait

The disease is present in muscle. Depending on the effect, degeneration of muscle may take place. Alternatively, recovery following exercise may be deteriorated.

Breed dependence

For this test samples from all breeds are accepted.

Sample type

For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.


An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.

An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.

An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.


This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).

Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease


Code V576

Porcine Stress Syndrome (PSS)

€ 25,18 (excl. VAT)