Enterotoxigenic Escherichia coli (ETEC) is a disease causing type of bacteria that can easily spread among stable- and littermates. The ETEC can be classified based on different fimbriae types present on the surface of the bacteria, from which F4 (K88) and F18 are the most important subtypes. The fimbriae are used by the E. Coli to attach to the intestinal cells of the host and after adhesion the bacteria release enterotoxins and causes diarrhoea. The susceptibility of a host to the adhesion by the bacteria can be genetically determined.
There are two F18 fimbriae types; F18ab and F18ac. The F18ab fimbrial subtype can also be colonized by other E. Coli strains, namely the Shiga toxin–producing E. coli (STEC) and verotoxin-producing E. coli (VTEC).
Test specific information
Susceptibility of a host to ETEC-F18 can be genetically determined by this DNA test.
The genetic factor is continuously present, and will always be visible.
Turn Around Time
The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.
Location of disease or trait
For this test samples from all breeds are accepted.
For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.
An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.
An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.
This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).
Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.
Severity of Disease